“We’re not going to change from our plans, so there will be a lot of changes for next week, which are already pre-planned,” he said.
“And that is to give the squad a run by the end of the Georgia game and that’s what we will be doing.
“We will continue to build the depth and continue to work hard.”
Ireland head coach Andy Farrell felt his side were worthy winners, while there were relatively upbeat assessments on the fitness of skipper Sexton and absent duo Jacob Stockdale and Iain Henderson.
“I thought it was better than a 10-point lead at half-time and then second half a little bit disjointed at times but I thought Wales did a good job on our speed of ball and breakdown, it just stopped a little bit of continuity,” said Farrell.
“Overall I thought it was a dominant performance and the scoreline is a reflective one, I would have thought.”
Sexton limped off with a hamstring problem after kicking his second penalty of the evening, while Henderson and Stockdale were late withdrawals due to an unspecified medical issue and a calf injury respectively.
Farrell expects Stockdale and Henderson to be available to face England next week.
Sexton, meanwhile, remains optimistic about running out at Twickenham.
“It doesn’t feel too serious. Just very frustrating. I thought initially I was going to be able to run it off but unfortunately not,” said Sexton.
“Tomorrow I will probably get a scan and see if there is any little damage done but I am still hopeful for next week.”
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